Kunal Sharma

What are BDNF… …and how can we increase them in our bodies

February, 2018
The Master Responds

BDNF is ‘brain derived neurotrophin factor’. Neurotrophins are proteins that help in the survival, development, and function of neurons. These neurotrophins are secreted proteins that are capable of signalling cells to survive, differentiate, and grow.

Exercise is one of the finest ways to increase BDNF.

In exercise our muscles pump iron but our cells pump out something else, especially our brain cells. Scientists, like Spiegelman, have found that a particular chemical gets produced by the brain after exercise which helps in neuron firing as well as in the prevention of diseases like Alzheimer's and Parkinson's.

Avoid refined sugars. Sugar kills brain cells and promotes cancerous cells. Research shows a diet rich in sugar reduces the production of the brain chemical BDNF. Well, without BDNF our brain cannot form new memory and cannot learn much of anything. Levels of BDNF are particularly low in people with diabetics and prediabetic conditions. And after that low levels of BDNF begin contributing to insulin resistance, which leads to type 2 diabetes and metabolic syndrome, which eventually leads to a host of other health problems. Once that happens, your brain and body are in a destructive cycle that is difficult, if not possible at all, to reverse.

Try to follow fasting on a daily basis. Intermittent fasting helps not only to reduce body weight but also it helps in the cognitive function of brain by reducing oxidative

stress. Studies show intermittent fasting increases the ratio of Glutathione which is one of the most important antioxidants for the brain, and levels of HNF and nitrotyrosine get reduced. Controlled meals, skipping or intermittent fasting really helps the brain in terms of eliminating brain fatigue, dementia, and mood swings. Studies show that consuming excess of calories reduces the flexibility of synapses and increases the chances of cells to damage by causing the formation of free radicals. Intermittent fasting always protects the brain from oxidative stress.


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